Precision Medicine and Health Consortium (PMHC)
The Precision Medicine and Health Consortium capitalizes on the expertise within the scientific community, health systems, payor industry and others to make novel discoveries and therapeutic advances in precision medicine, and translate these to improve healthcare.
The PMHC joins together faculty with a common purpose and connects faculty with expertise in precision medicine to address health problems using an interdisciplinary approach. It is our belief that a interdisciplinary group will more quickly advance research, educational, and outreach activities.
Members of the PMHC also bridge the gap between genetic research discoveries and application in patient care. Precision Medicine is a national priority and this group strives to keep on the forefront of this evolving field.
A College of Pharmacy internal grant has been awarded to the project, "Enhance Comprehensive Pharmacist Services to Improve Patient Health: Creating a 21 st Century Precision Medicine Intensive Care Unit (ICU)."
The focus of the project is on sedation in intubated patients and it aims to identify actionable genetic variants in ICU patients and evaluate the relationship between genotypes and drug efficacy as well as adverse drug reactions (ADR) in a real-world setting at the bedside.
As part of the Moonshot Initiative, NCI has announced the funding of a U54 grant with interactive projects to the University of Minnesota and Mayo Clinic.
The grant is entitled “Overcoming Drug Resistance in Multiple Myeloma”. The project from the University of Minnesota is led by Dr. Brian Van Ness.
A Precison Medicine themed issue of Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy was published Sept. 20th, 2017. The issue was edited by Jeffrey R. Bishop an Vicki L. Ellingrod. Read the issue
The NIH released the initial research protocol for the All of Us Research Program. Read the full announcement and the frequently asked questions releases.
Wylie Burke, M.D., Ph.D.
Wednesday, April 12, 2017
"Working Together on Pharmacogenetics: Report on a Tribal-University Partnership"
Fairview Health Services is working with a local genetics research firm to determine if DNA tests can steer patients to more effective treatment for high blood pressure.
A new project titled "U-PGx" aims to make effective treatment optimization accessible to every European citizen. The U-PGx consortium will examine whether pre-emptive genotyping of an entire panel of genetic markers is cost-effective and results in a better outcome for patients.
A new resource is available on PharmGKB to help researchers and clinicians more easily and quickly understand CPIC recommendations and how to find supporting information on the PharmGKB website.