Pharmacogenomic Project on Sedation in Intubated Patients Receives Internal Funding

A College of Pharmacy internal grant has been awarded to the project, "Enhance Comprehensive Pharmacist Services to Improve Patient Health: Creating a 21 st Century Precision Medicine Intensive Care Unit (ICU)."

The focus of the project is on sedation in intubated patients and it aims to identify actionable genetic variants in ICU patients and evaluate the relationship between genotypes and drug efficacy as well as adverse drug reactions (ADR) in a real-world setting at the bedside.

The Co-Principal Investigators are Debra J. Skaar, PharmD, FCCM, Associate Professor of Experimental & Clinical Pharmacology and Craig R. Weinert, MD, MPH, Professor of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine.  

The Co-Investigators are Zachary Rivers, PharmD, Graduate Student in Social and Administrative Pharmacy (SAPh), University of Minnesota College of Pharmacy and Clinical Pharmacist, M Health, Rui Zhang, PhD, Assistant Professor, Department of Pharmaceutical Care & Health Systems, College of Pharmacy, and Institute for Health Informatics, University of Minnesota, Shellina Scheiner, PharmD, BCGP, Assistant Professor of Experimental & Clinical Pharmacology, University of Minnesota College of Pharmacy and Clinical Pharmacist in Geriatrics, Greg Beilman, MD, Deputy Chair of Surgery, Owen H and Sarah Wangensteen Chair, Executive Medical Director of M Health Critical Care Program, COL (ret), US Army Reserves and Pamala A. Jacobson, PharmD, FCCP, Professor of Experimental & Clinical Pharmacology.

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