Genomic Resources

Groups

Consortium on Law and Values in Health, Environment & the Life Sciences
The Consortium conducts original research, serves students and faculty, and advances public dialogue and understanding on emerging issues at the intersection of science and society.

Epigenetics Consortium at the University of Minnesota
The newly established Epigenetics Consortium at the University of Minnesota aims to strengthen the epigenetics research at our university and establish the UMN as a major key player in this

Institute of Personalized Medicine - College of Pharmacy (PUMA-IPM)
PUMA-IPM is a distinctive research group of investigators from various disciplines dedicated to advance the field of pharmacogenomics to help prescribe right medicine at the right dose and thus improve the safety and efficacy of currently prescribed medications.

Pharmacogenomics ​Research ​Network (PGRN)
The mission of the Pharmacogenomics Research Network (PGRN) is to catalyze and lead research in precision medicine for the discovery and translation of genomic variation influencing therapeutic and adverse drug effects. To this end, the PGRN hosts various activities that stimulate collaborative research in pharmacogenomics and precision medicine.

Research Resources

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Videos

CPIC videos that describe the role of the gene(s) and the impact of genetic variation on drug response, provide an overview of the genotype-phenotype terminology and classification, and summarize the CPIC recommendations for changing drug dose or drug choice based on patient diplotypes.

Clinical Sequencing Exploratory Research Program
Multidimensional research in whole genome sequencing initiated by the National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI).

CYPallele Nomenclature Website 
Provides information on major cytochrome P450s and their genetic polymorphism. 

dbSNP home Page 
The Single Nucleotide Polymorphism database (dbSNP) is a public-domain archive for a broad collection of simple genetic polymorphisms.

FDA Genomic Marker Table 
The table from FDA’s website listing FDA-approved drugs with pharmacogenomic information in their labels. 

iGeneTRAIN
iGeneTRAIN aims to coordinate genetic and other patient data and expertise from sites across the world engaged in clinical and research transplant programs.

International HapMap Project 
The goal of the International HapMap Project is to develop a haplotype map of the human genome, the HapMap, which will describe the common patterns of human DNA sequence variation. The HapMap is expected to be a key resource for researchers to use to find genes affecting health, disease, and responses to drugs and environmental factors.

PharmGKB 
The PharmGKB is a pharmacogenomics knowledge resource that encompasses clinical information including dosing guidelines and drug labels, potentially clinically actionable gene-drug associations and genotype-phenotype relationships.

PharmGKB-drug-dosing guidelines 
These dosing guidelines take into consideration patient genotype and have been published by the Clinical Pharmacogenetics Implementation Consortium CPIC, the Royal Dutch Association for the Advancement of Pharmacy - Pharmacogenetics Working Group DPWG (manually curated by PharmGKB), or other professional society PRO (manually curated by PharmGKB).

PharmGKB GeneticTest List 
This is a non-comprehensive list of genetic tests with pharmacogenetics relevance (manually curated by PharmGKB). 

Public Health Genomics Knowledge Base
This is an online, searchable database of published scientific literature, CDC resources, and other material that addresses the translation of genomic discoveries into improved health care and disease prevention. 

Education

Pharmacogenomics Course PHAR 6224: Genetic Basis for Variability in Drug Response
An elective course Spring 2016 designed to introduce the theory and practice of pharmacogenomics. The goal of the course is to give students an understanding of the principles of human genetics and genomics as they apply to improving the problems in drug therapy optimization and patient care.

Facilities

Clinical Pharmacology Analytical Services Lab
Develop, validate, and maintain state of the art quantitative assays to support research and clinical care for researchers and clinicians. Expertise in pharmacology, pharmacokinetics, pharmacodynamics, genetics, and genomics to help investigators develop scientific protocols and to help clinicians optimize drug therapy in patients.

University of Minnesota Genomics Center Core Facility 
The Genomics Center provides genomics research services committed to advancing genomics in Minnesota. The UMGC maintains and acquires state-of-the-art instrumentation and offers an array of services including sequencing, expression, genotyping, nucleic acid extraction and related support